Heterocycles p. 1015 - 1020 (2000)
Update date:2022-09-26
Topics:
Matsumoto, Kiyoshi
Iida, Hirokazu
Lown, J. William
A synthetic procedure is described for conjugating polyaminoalkyl groups to the pyrrolo[2,1-c][1,4]benzodiazepine pharmacophore in order to alter its characteristic DNA sequence binding preference. To this end S(N)Ar reactions of 2-nitro-5-fluorobenzoate
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(2000)Doi:10.1021/ja00714a043
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(2000)Doi:10.1055/s-2000-6507
(2000)Doi:10.1007/BF00910242
(1970)Doi:10.1515/znb-2008-0811
(2008)
