Synthese symmetrischer, makrocyclischer phosphoramidite

Article abstract of DOI:10.1080/10426509808045481

The reaction of phosphorous ester diamide 1 with bisphenol 2 did not lead to the expected asymmetric macrocycle 3 but instead in low yield to the symmetric macrocycle 4. The structure of the trans-isomer of 4 was determined by X-ray diffractometry. The same phenomenon was observed in the reaction of phosphorous ester diamide 5 with bisphenol 6, affording the symmetric macrocycle 7 as a mixture of cis-and trans-isomers. These results can only be explained by transesterification reactions which occur prior to the esterification of the phosphorous amide function.

Full text of DOI:10.1080/10426509808045481

Phosphorus, Sulfur, and Silicon and the Related Elements
ISSN: 1042-6507 (Print) 1563-5325 (Online) Journal homepage: http://www.tandfonline.com/loi/gpss20
SYNTHESE SYMMETRISCHER, MAKROCYCLISCHER
PHOSPHORAMIDITE
I. Bauer , W. D. Habicher , P. G. Jones , H. Thönnessen & R. Schmutzler
To cite this article: I. Bauer , W. D. Habicher , P. G. Jones , H. Thönnessen & R. Schmutzler
(1998) SYNTHESE SYMMETRISCHER, MAKROCYCLISCHER PHOSPHORAMIDITE, Phosphorus,
Sulfur, and Silicon and the Related Elements, 143:1, 19-31, DOI: 10.1080/10426509808045481
To link to this article: http://dx.doi.org/10.1080/10426509808045481
Published online: 04 Oct 2006.
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Date: 06 June 2016, At: 19:42