Preparation and reactions of 2.2.4-trimethylimidazoline-5-thion (joint action of sulfur and ammonia upon ketones, LXX. Action of sulfur and ammonia upon acetone, II)

Article abstract of DOI:10.1007/BF00910236

2.2.4-Trimethylimidazoline-5-thione (1) is obtained in good yields by the joint action of a large excess of sulfur and ammonia upon acetone at temperatures around -60° C in presence of certain accelerators. 1 gives a Cu(I)-salt and is converted by alkaline H₂O₂ to 2.2.4-trimethylimidazoline-5-one (3). 1 reacts fairly smoothly with primary and secondary amines to yield 2.2.5-trimethyl-4-alkylamino-2 H-imidazoles (4-12).