Tetrahedron Letters p. 8347 - 8350 (2006)
Update date:2022-08-03
Topics:
Chang, Meng-Yang
Wu, Tsun-Cheng
Lin, Chun-Yu
Hung, Ching-Yi
Several 1-substituted phenyl-(4-phenylpiperidin-4-yl)methanones are synthesized in modest overall yields starting from the reaction of different 1-substituted 4-benzhydrylidenepiperidines via CAN-mediated rearrangement. This facile strategy was also used to synthesize meperidine analog.
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