Synthesis of 2-alkylthio-substituted 4-oxo-3-p-tolyl-3,4,5,6-tetrahydrospiro(benzo[h]quinazoline-5,1′- cycloalkanes)

Article abstract of DOI:10.1007/BF02251821

Reaction of 4-amino-3-carbethoxy-1,2-dihydrospiro(naphthalene-2,1′-cycloalkanes) with p-tolylisothiocyanate gave 4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydro(benzo[h]quinazoline-5,1′- cycloalkanes) which could be alkylated using various halo compounds t