Synthesis, DNA binding, and biological evaluation of synthetic precursors and novel analogues of netropsin

DOI: 10.1021/jm00125a024

Source and publish data:

Journal of Medicinal Chemistry p. 1074 - 1083 (1989)

Update date:2022-09-26

Topics:

Authors:

Debart Debart

Perigaud

Gosselin

Mrani Mrani

Rayner Rayner

Le Ber Le Ber

Auclair Auclair

Balzarini

De Clercq

Paoletti

Imbach Imbach

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Article abstract of DOI:10.1021/jm00125a024

A series of oligopeptides have been synthesized that are structurally related to the natural agent netropsin. The binding constants to double-stranded polynucleotides as well as the cytostatic activity against both murine human tumor cell lines and the in

Full text of DOI:10.1021/jm00125a024

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