A novel one-step conversion of α,β-epoxy ketones to o-dichlorobenzaldehydes by the Vilsmeier reaction

Article abstract of DOI:10.1016/00404-0399(50)1105Q-

A novel, versatile one-step synthesis of o-dichlorobenzaldehydes has been developed. Acyclic α,β-epoxy ketones undergo the Vilsmeier reaction to afford o-dichlorobenzenemono- and dicarboxyaldehydes whereas cyclic α,β-epoxy ketones gave des and chlorobenzenedicarboxyaldehydes.