Journal of Medicinal Chemistry p. 36 - 40 (1985)
Update date:2022-08-03
Topics:
Chadha, Vijay K.
Leidal, Kevin G.
Plapp, Bryce V.
3-Substituted thiolane oxides (methyl, n-butyl, n-hexyl, and phenyl) were prepared and tested as inhibitors of horse, monkey, and rat liver alcohol dehydrogenases and of ethanol metabolism in rats.These compounds inhibit alcohol oxidation in an uncompetit
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