Bioorganic and Medicinal Chemistry Letters p. 2791 - 2794 (1996)
Update date:2022-08-03
Topics:
Gehanne, Sylvie
Piga, Elisabetta
Andreotti, Daniele
Biondi, Stefano
Pizzi, Domenica
This article describes studies carried out on the synthesis and biological activity of 4-ureido trinems 1 obtained by the condensation of various isocyanates and the intermediate 6. Among others, 4-N-methyl-N'-alkyl ureido trinems showed a promising antimicrobial activity against Gram-negative bacteria.
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