Synthesis and antibacterial activity of 4-ureido trinems

DOI: 10.1016/S0960-894X(96)00515-X

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2791 - 2794 (1996)

Update date:2022-08-03

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Authors:

Gehanne, Sylvie

Piga, Elisabetta

Andreotti, Daniele

Biondi, Stefano

Pizzi, Domenica

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Article abstract of DOI:10.1016/S0960-894X(96)00515-X

This article describes studies carried out on the synthesis and biological activity of 4-ureido trinems 1 obtained by the condensation of various isocyanates and the intermediate 6. Among others, 4-N-methyl-N'-alkyl ureido trinems showed a promising antimicrobial activity against Gram-negative bacteria.

Full text of DOI:10.1016/S0960-894X(96)00515-X

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