Chemical and Pharmaceutical Bulletin p. 1270 - 1280 (2000)
Update date:2022-08-03
Topics:
Itoh, Fumio
Yoshioka, Yoshio
Yukishige, Koichi
Yoshida, Sei
Ootsu, Koichiro
Akimoto, Hiroshi
The glutamic acid moiety of N-[4-[3-(2,4-diamino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)propyl]benzoyl]-L-glutam ic acid (1b, TNP-351) and the related compound (1a), was replaced with various N(ω)-acyl-, sulfonyl-, carbamoyl- and aryl-2,ω-diaminoalkanoic acids,
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