Tetrahedron Letters p. 8191 - 8194 (1998)
Update date:2022-08-05
Topics:
Pan, Shifeng
Wang, Guoping
Schinazi, Raymond F.
Zhao, Kang
Isoxazoline rings have been successfully connected to imidazo<1,2-a>pyridine derivatives via carbon-carbon bonds for the synthesis of new C-nucleoside analogs 7 and 8.These two isomers, possessing altered positions of nitrogen and oxygen atoms, can be formed through dipolar cycloaddition reactions of the appropriate olefins and nitrile oxides.
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