
Tetrahedron p. 6927 - 6934 (1994)
Update date:2022-08-05
Topics:
Moris, Francisco
Gotor, Vicente
N-protected aminoacyl acetoxime esters are useful agents for enzymatic aminoacylation of 2'-deoxy- and ribo-nucleosides. In both cases, 5'-O- derivatives can be prepared if the lipase used is SP 435 (from Candida antarctica) whereas 3'-O-isomers from 2'-deoxynucleosides are obtained with Pseudomonas cepacia.
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