Synthesis of N-methyl-4-pyridyl-1,2,3,4-tetrahydroisoquinolines via a Pictet-Spengler cyclisation

DOI: 10.1002/jhet.5570370417

Source and publish data:

Journal of Heterocyclic Chemistry p. 767 - 771 (2000)

Update date:2022-08-03

Topics:

Authors:

Prat Prat

Bureau Bureau

Daveu Daveu

Levacher

Dupas Dupas

Queguiner

Bourguignon

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Article abstract of DOI:10.1002/jhet.5570370417

The synthesis of N-methyl-4-pyridyl-1,2,3,4-tetrahydroisoquinolines (6a,b,c) was achieved via a Pictet-Spengler cyclization of an activated amino group derivatized in a carbamate form. The obtained compounds have been designed as potential serotonin analo

Full text of DOI:10.1002/jhet.5570370417

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