Azobenzene-containing, peptidyl α-ketoesters as photobiological switches of α-chymotrypsin

Article abstract of DOI:10.1016/S0040-4020(00)00883-8

Three photoswitchable, peptidomimetic inhibitors of α-chymotrypsin have been synthesised. The compounds comprise an azobenzene, an α-ketoester and L-phenylalanine. The compounds were photoisomerised to give enriched states of the (E) and (Z) isomers and t