AROMATIC HETEROANNULATION VIA ORTHO LITHIATION-CYCLIZATION OF N-ACYL-2-BROMOBENZAMIDES

DOI: 10.1016/S0040-4039(00)95178-5

Source and publish data:

Tetrahedron Letters p. 275 - 278 (1989)

Update date:2022-07-30

Topics: Cyclization

Authors:

Hendi, Mukta S.

Natalie, Kenneth J. Jr.

Hendi, Shivakumar B.

Campbell, James A.

Greenwood, Thomas D.

Wolfe, James F.

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Article abstract of DOI:10.1016/S0040-4039(00)95178-5

N-acyl-2-bromobenzamides participate in metal-halogen exchange with n-BuLi to form N-acyl-2-lithiobenzamides, which undergo cyclization to afford 3-alkylidenephtalimides.

Full text of DOI:10.1016/S0040-4039(00)95178-5

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