Journal of the Chemical Society. Perkin transactions I p. 2619 - 2622 (1996)
Update date:2022-08-05
Topics:
Bracher, Franz
Schulte, Brigitte
A straightforward approach to both enantiomers of lasiodiplodin 1 is described utilizing (S)-2-(2-hydroxypropyl)-1,3-dithiane 3 as a chiral building block. The key step is a Pd0-catalysed cross coupling of an arene trifluoromethanesulfonate with a 9-alkyl-9-borabicyclo[3.3.1]nonane derivative. The two enantiomers 1 and ent-1 have been obtained in an enantiodivergent manner by macrolactonization of the hydroxy acid 10 with either Gerlach's modification of the Corey lactonization or a Mitsunobu lactonization.
View MoreVanderArk International Limited
Contact:86-10-82437576
Address:Qing He
Chengdu Aslee Biopharmaceuticals, Inc
Contact:18608018419
Address:Chengdu Aslee Biopharmaceuticals, Inc
shijiazhuang baisheng chem co.; ltd
Contact:86-0311-80790826
Address:shijiazhuang hebei
QINGDAO TAOSIGN INTERNATIONAL TRADE CO.,LIMITED
Contact:+86-0532-82683616
Address:RM1402, Doublestar Seacoase 7#, No. 5 Guizhou Road, Qingdao, Shandong, China
Chengdu ZY Biochemical Technology Co., LTD
Contact:0086-28-88680086
Address:170 Qingpu Road, Shouan Town, Pujiang County
Doi:10.1021/jo00968a012
(1972)Doi:10.1021/jf0010578
(2001)Doi:10.1016/S0040-4020(01)91411-5
(1985)Doi:10.1246/cl.2001.60
(2001)Doi:10.1246/cl.2001.36
(2001)Doi:10.1016/j.chempr.2020.05.017
(2020)
