Journal of Organic Chemistry p. 2292 - 2303 (1994)
Update date:2022-08-05
Topics:
Desmaeele, Didier
d'Angelo, Jean
An enantioselective synthesis of (+)-aspidospermidine (1b) has been developed.The key strategic element was the stereocontrolled elaboration of quaternary carbon centers through the asymmetric Michael reaction, using chiral imines under neutral conditions
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