Stereocontrolled Elaboration of Quaternary Carbon Centers through the Asymmetric Michael Reaction Using Chiral Imines: Enantioselective Synthesis of (+)-Aspidospermidine

DOI: 10.1021/jo00088a008

Source and publish data:

Journal of Organic Chemistry p. 2292 - 2303 (1994)

Update date:2022-08-05

Topics:

Authors:

Desmaeele, Didier

d'Angelo, Jean

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00088a008

An enantioselective synthesis of (+)-aspidospermidine (1b) has been developed.The key strategic element was the stereocontrolled elaboration of quaternary carbon centers through the asymmetric Michael reaction, using chiral imines under neutral conditions

Full text of DOI:10.1021/jo00088a008

Products guided by the article

Product name:dl-aspidospermidine

Cas No:32975-45-4

R&D Labs maybe for 32975-45-4

QINGDAO TAOSIGN INTERNATIONAL TRADE CO.,LIMITED

Contact:+86-0532-82683616

Address:RM1402, Doublestar Seacoase 7#, No. 5 Guizhou Road, Qingdao, Shandong, China
Penglai Qianwei Chemical Co., Ltd.

Contact:86-535-3357802

Address:Shahelu (north), Penglai, Shandong, China
ORCHID CHEMICAL SUPPLIES LTD

website:http://www.orchid-chem.com

Contact:+86-571-85395792

Address:607, North Zhongshan Road, Hangzhou 310000 China
Zhejiang Quzhou Jiancheng Silicone Co., Ltd.(Shanghai Jiancheng Industial and Trade Co, Ltd)

Contact:18957018777 +86-570-3888777

Address:The company production base address： Quzhou City, Zhejiang Province high-tech industrial park Nianhua Road 37
Yangzhou Zhongbao Pharmaceutical Co.,Ltd

Contact:+86-514-88290838

Address:Jiangsu Baoying county economic develpment zone in baoying avenue91

Relevant to this article

Doi:10.1016/S0040-4020(01)82670-3
(1969)
Doi:10.1021/ja00738a028
(1971)
Design, Synthesis, Biological Activities, and 3D-QSAR of New N,N'-Diacylhydrazines Containing 2-(2,4-dichlorophenoxy)propane Moiety

Doi:10.1111/j.1747-0285.2011.01205.x
(2011)
Synthetic exploitation of halogenated alkenes containing EWG: Benzotriazole-mediated synthesis of benzoazetines and thermal transformations

Doi:10.1039/c4ra01425a
(2014)
Synthesis and evaluation of a series of aminocyanopyridines as antimicrobial agents

Doi:10.1007/s00044-009-9273-x
(2011)
Vortex fluidic promoted Diels-Alder reactions in an aqueous medium

Doi:10.1016/j.tetlet.2014.02.077
(2014)

Article Doi