Research on potentially bioactive Aza and Thiaza polycyclic compounds containing a bridgehead nitrogen atom. III. Synthesis and antimicrobial activity of some 1,4-benzothiazines and pyrrolobenzothiazines

Article abstract of DOI:10.1002/jhet.5570370634

Cyclization reactions of N-(2,2-dialkoxyethyl)-1,4-benzothiazine lactams 2 and 1,4-benzothiazine-sulfones 10 lead to the corresponding pyrrolo[1,2,3-de]-1,4-benzothiazines 4 and 12, respectively, by using the dioxane/p-toluenesulfonic acid or polyphosphor