Gas-phase pyrolysis of 4-amino-3-allylthio-1,2,4-triazoles: A new route to [1,3]thiazolo[3,2-b][1,2,4]triazoles

Article abstract of DOI:10.1039/b007638o

A short route to the [1,3]thiazolol[3,2-b]-[1,2,4]triazole ring system in moderate overall yield was provided by an unusual pyrolysis sequence. The carbon atoms in the fused triazole and thaizole rings were derived from a 4-aminotriazole-3-thione unit and allyl groups. Dry-flash chromatography was carried out on silica gel using a hexane-ethyl acetate gradient as eluent.