Synthesis and antiviral activity of novel isonucleoside analogs

DOI: 10.1021/jm00061a013

Source and publish data:

Journal of Medicinal Chemistry p. 1221 - 1229 (1993)

Update date:2022-08-03

Topics:

Authors:

Tino Tino

Clark Clark

Field Field

Jacobs Jacobs

Lis Lis

Michalik

McGeever-Rubin

Slusarchyk

Spergel Spergel

Sundeen Sundeen

Tuomari Tuomari

Weaver Weaver

Young Young

Zahler Zahler

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Article abstract of DOI:10.1021/jm00061a013

A series of branched-chain sugar isonucleosides was synthesized and evaluated for antiviral activity against herpesviruses. The preparation of homochiral [3S-(3α,4β,5α)]-2-amino-1,9-dihydro-9-[tetrahydro-4,5- bis(hydroxymethyl)-3-furanyl]-6H-purin-6-one (

Full text of DOI:10.1021/jm00061a013

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Product name:3-deoxy-3-(hydroxymethyl)-1,2-O-(1-methylethylidene)-5-O-(phenylmethyl)-α-D-ribofuranose

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