Tetrahedron Letters p. 51 - 54 (1998)
Update date:2022-07-30
Topics:
Kato-Toma, Yoko
Imajo, Seiichi
Ishiguro, Masaji
Molecules mimicing class C β-lactamase catalytic residues were synthesized to study the effect of proximal positioning of serine, lysine and tyrosine side chains on their pKa values. The three amino acid side chains were mimicked by hydroxymethyl group, a
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