Insights into long-range structural effects on the stereochemistry of aldol condensations: A practical total synthesis of desoxyepothilone F

DOI: 10.1021/ja010039j

Source and publish data:

Journal of the American Chemical Society p. 5249 - 5259 (2001)

Update date:2022-08-03

Topics:

Authors:

Chul Bom Lee

Zhang Zhang

Chappell

Stachel Stachel

Chou Chou

Guan Guan

Danishefsky

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/ja010039j

A processable total synthesis of a potent antitumor agent, desoxyepothilone F (dEpoF, 21-hydroxy-12,13-desoxyepothilone B, 21-hydroxyepothilone D), has been accomplished. The route is highly convergent. The new technology has also been applied to a total

Full text of DOI:10.1021/ja010039j

Products guided by the article

Product name:ethyl 4-(diphenylphosphinoylmethyl)thiazole-2-carboxylate

Cas No:349655-00-1

R&D Labs maybe for 349655-00-1

ZHIJIANG ZENVA SINO COMMERCE AND TRADE CO., LTD.

website:http://www.zenvasino.com

Contact:+86-138-72658998

Address:Shibeishan Road,Zhijiang, Hubei, China
Nanjing Ruizhi Industry & Technologh Co.，Ltd.

Contact:+86-25-86808110

Address:441-4-A5,NO.12 Longzang Avenue,Yuhuatai District,210039,Nanjing
jiangsu senxuan pharmaceutical and chemical co.,ltd

Contact:86-523-87982810

Address:hongqiao industrial zone,taixing,jiangsu china
Shanghai Norky Pharmaceutical Co., LTD.

website:http://www.norkypharm.com

Contact:86-21-61075300

Address:1165 Jiangning Road, Office 1502, Shanghai, China
Jintan City Mego Chemical Co., Ltd

Contact:+86-0519-82814387

Address:23# Dengguan Town, Jintan, Jiangsu Province, China

Relevant to this article

Doi:10.1016/S0022-328X(00)82929-0
(1972)
Facile generation of [bis(2-pyridyldimethylsilyl)methyl]lithium and its reaction with carbonyl compounds. New method for the stereoselective synthesis of vinylsilanes

Doi:10.1016/S0040-4020(01)00348-9
(2001)
Organotin(IV) complexes of 4,6-dimethylpyrimidine-2-thione, Me₂PymtH. Preparation, characterization and crystal structure determination of cis-[Ph₂Sn(Me₂Pymt)₂] and [Ph₃Sn(Me₂Pymt)]

Doi:10.1016/S0277-5387(02)00996-8
(2002)
Aminoacids in the synthesis of heterocyclic systems: The synthesis of triazinoquinazolinones, triazepinoquinazolinones and triazocinoquinazolinones of potential biological interest

Doi:10.3390/60300267
(2001)
Selective intercalation of charge neutral intercalators into GG and CG steps: Implication of HOMO-LUMO interaction for sequence-selective drug intercalation into DNA

Doi:10.1021/ja003956i
(2001)
Synthesis of lariat ether carboxylic acids based on dibenzo- 16-crown-5

Doi:10.1002/jhet.5570380201
(2001)

Article Doi