Bioorganic and Medicinal Chemistry Letters p. 4472 - 4476 (2016)
Update date:2022-07-30
Topics:
Ren, Jing
Xu, Wei
Tang, Le
Su, Minbo
Chen, Danqi
Chen, Yue-Lei
Zang, Yi
Li, Jia
Shen, Jingkang
Zhou, Yubo
Xiong, Bing
Menin is an essential oncogenic cofactor for mixed lineage leukemia (MLL)-mediated leukemogenesis, functioning through its direct interaction with MLL1 protein. Therefore, targeting the menin–MLL1 protein–protein interface represents a promising strategy
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