Helvetica Chimica Acta p. 887 - 897 (1986)
Update date:2022-07-30
Topics:
Maag, Hans
Locher, Rita
Daly, John J.
Kompis, Ivan
Based on a computer-assisted analysis of the three-dimensional structure of the binary complex of E.coli dihydrofolate reductase (DHFR) with methotrexate, 5-(N-arylnortropan-3-yl)- and 5-(N-arylpiperidin-4-yl)-2,4-diaminopyrimidines 2 and 4 were designed
View MoreContact:+86-371-55981030
Address:Room 1571, Macalline Soho, No.1, Shangdu Road, Zhengzhou, Henan
Anhui Biochem United Pharmaceutical Co., Ltd.
Contact:0086 551 5167062 / 5228268
Address:No. 30 Hongfeng Road, Hi-Tech Development Zone, Hefei (230088), China
Shanghai Collins & Paulson Pharmaceuticals Co., Ltd.
Contact:15201714675
Address:Room A647-18, Building No. 2, 351 Guoshoujing Road, Shanghai Free Trade Zone
website:http://www.afinechem.com
Contact:+86-571-85134551
Address:No. 206 Zhen Hua Road, Hangzhou 310030, Zhejiang, China
Contact:+86-10-59484199
Address:No.58-A1026 Liangguan Street
Doi:10.7164/antibiotics.24.767
(1971)Doi:10.1021/ja01145a050
(1951)Doi:10.1016/0039-128X(63)90016-3
(1963)Doi:10.1021/jm00276a013
(1972)Doi:10.1002/ardp.19883210708
(1988)Doi:10.1016/S0040-4039(01)00644-X
(2001)