18-Substituted Steroids. Part 8. An Improved Synthesis of 11β,18,21-Trihydroxypregn-4-ene-3,20-dione ('18-Hydroxycorticosterone')

DOI: 10.1039/P19810000703

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 703 - 705 (1981)

Update date:2022-08-04

Topics:

Authors:

Kirk, David N.

Slade, Christopher J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/P19810000703

'18-Hydroxycorticosterone' (1) has been prepared from 11β-formyloxy-20-hydroxypregn-4-en-3-one (6) by application of the 'hypoiodite' series of reactions , followed by acetoxylation at C-21 by lead tetra-acetate in acetic acid.Alkaline hydrolysis then gave 18-hydroxycorticosterone.

Full text of DOI:10.1039/P19810000703

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:diginanetriol-(3β.11α.20α_F)

Cas No:3676-17-3

R&D Labs maybe for 3676-17-3

Hangzhou Neway Chemicals Co., Ltd.

Contact:+86-571-85095566

Address:Room 803, Qinglian Bldg, No 139 Qingchun Road, Hangzhou, Zhejiang China
Hangzhou Gangjin Chemical Co.,Ltd.(expird)

Contact:+86-571-85109780

Address:707 Zhejiang Minhang Bldg., No.290 Zhongshan North Road, Hangzhou 310003, China
Hangzhou Taiyan Trading Co., Ltd(expird)

Contact:+86-13777583958

Address:NO.63, Xingyi Street, Xihu District, Hangzhou, Zhejiang, China
Shanghai Maxchemco Chemical Industry Co., Ltd.

Contact:(86)21-51079223

Address:No.1305-8, B241, the Ecust Park, Huajing Road, Xuhui District, Shanghai
Clearsynth Labs Limited

Contact:+91 - 22 - 26355700

Address:17, Lotus Business Park, Andheri West

Relevant to this article

REGIOINTEGRITY OF CARBANIONS DERIVED BY SELECTIVE METALATIONS OF DIMETHYLPYRIDINES AND -QUINOLINES

Doi:10.1016/S0022-328X(00)82948-4
(1981)
Investigating the spectrum of biological activity of ring- substituted salicylanilides and carbamoylphenylcarbamates

Doi:10.3390/molecules15118122
(2010)
A facile synthesis of 5-amino-[1,2,3]triazolo[5,1-a]isoquinoline derivatives through copper-catalyzed cascade reactions

Doi:10.1039/c3ob41774c
(2013)
Design, synthesis, and evaluation of potent Wnt signaling inhibitors featuring a fused 3-ring system

Doi:10.1016/j.ejmech.2015.11.026
(2016)
Synthesis of a new spiropyran based on [60]fullerene unit

Doi:10.1081/SCC-120004254
(2002)
Palladium-catalyzed reduction of ketones with ⁿBu₂SnH₂

Doi:10.1016/S0040-4039(02)00078-3
(2002)

Article Doi