A convenient synthesis of chiral, non-racemic [4aS,8aR]- 5,5,8a-trimethyl octahydro-2,2-(1,3-dioxolane)-naphthalene

Article abstract of DOI:10.1080/00397910008087164

(-)-(4aS,8aR)-5,5-8a-trimethyl-trans-decaline 1 was prepared in a stereoespecific synthesis of 4 steps and 38% yield. The key- step involves an asymmetric Robinson annulation via Michael addition of chiral imine.

Full text of DOI:10.1080/00397910008087164

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Synthetic Communications: An
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A Convenient Synthesis
of Chiral, Non-Racemic
[4aS,8aR]-5,5,8a-Trimethyl
Octahydro-2,2-(1,3-Dioxolane)-
Naphthalene
Beatriz S.M. Tenius a & Evelyn K. Schroeder a
a Universidade Federal do Rio Grande do Sul,
Instituto de Quimica , 91501-970, Porto Alegre, RS,
Brazil
Published online: 04 Dec 2007.
To cite this article: Beatriz S.M. Tenius & Evelyn K. Schroeder (2000) A Convenient
Synthesis of Chiral, Non-Racemic [4aS,8aR]-5,5,8a-Trimethyl Octahydro-2,2-(1,3-
Dioxolane)-Naphthalene, Synthetic Communications: An International Journal
for Rapid Communication of Synthetic Organic Chemistry, 30:8, 1371-1378, DOI:
10.1080/00397910008087164
To link to this article: http://dx.doi.org/10.1080/00397910008087164
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