Synthons for biologically active compounds on the basis of naphthalene ozonolysis products

Article abstract of DOI:10.1134/S1070428006030109

Ozonolysis of naphthalene in aqueous methanol, followed by the reduction of peroxy compounds thus formed with potassium iodide in the presence of acetic acid, gave 3-methoxy-2-benzofuran-1(3H)-one. In the absence of water, the product was methyl o-formylbenzoate. The latter was used as a synthon for the preparation of aromatic analogs of (2E)-2,6-dimethyloct-2-ene-1,8-diol ethers which are effective juvenoids. Pleiades Publishing, Inc., 2006.

Full text of DOI:10.1134/S1070428006030109

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