Il Farmaco p. 689 - 693 (2001)
Update date:2022-09-26
Topics:
De M. Guarda
Perrissin, M
Thomasson, F
Ximenes
Galdino
Pitta
Luu-Duc, C
The synthesis and physicochemical properties of 4-butyl-2H-benzo[1,4]thiazin-3-one derivatives are described. These new compounds were synthesised by alkylation in 4-N position and acylation and/or alkylation of 6-NH2 by phase transfer catalysis. Acid hydrolysis of 6-alkylacylamino group yielded 6-alkylamino-4-butyl-2H-benzo[1,4]thiazin-3-ones. The antimicrobial in vitro activity was determined on five compounds. Copyright
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Doi:10.1016/S0040-4039(02)00505-1
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(2020)Doi:10.1248/cpb.54.591
(2006)Doi:10.1021/ja00906a008
(1963)Doi:10.1021/ic50126a038
(1973)Doi:10.1016/0223-5234(96)89169-0
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