A novel synthetic route to 1-aminoalkylphosphinic acids

Article abstract of DOI:10.1055/s-1994-25395

A 'one-pot' synthesis of various 1-aminoalkylphosphinic acids is described. They were obtained in high yield by the deprotection of the corresponding bis(trimethylsilyl) N-tritylaminoalkylphosphites. The latter were prepared by addition of bis(trimethylsilyl) phosphonite to a N-tritylalkanimine.