Tetrahedron Letters p. 1642 - 1645 (2018)
Update date:2022-07-31
Topics:
Grytsai, Oleksandr
Druzhenko, Tetiana
Demange, Luc
Ronco, Cyril
Benhida, Rachid
An effective, easy-to-handle, safe and inexpensive protocol is reported for the synthesis of 2-aminobenzoxazoles under Lewis acid activation, utilising cyanoguanidine as the cyanating reagent. An optimized procedure for the synthesis of 2-guanidinobenzoxazole and novel derivatives is also described.
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