Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 1. (±)-(3-Pyridinylbicycloheptyl)alkanoic acids

DOI: 10.1021/jm00110a006

Source and publish data:

Journal of Medicinal Chemistry p. 1790 - 1797 (1991)

Update date:2022-09-26

Topics:

Authors:

Bhagwat Bhagwat

Gude Gude

Cohen Cohen

Lee Lee

Furness Furness

Clarke Clarke

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00110a006

The design, synthesis, and in vitro pharmacology of a new class of compounds exerting both thromboxane receptor antagonist and thromboxane synthase inhibtory activities is described. [(3-Pyridinyl)bicycloheptyl]alkanoic acid 9 and its analogues, designed

Full text of DOI:10.1021/jm00110a006

Products guided by the article

Product name:Pentanoic acid, 5-(triphenylphosphoranylidene)-, potassium salt

Cas No:39647-97-7

R&D Labs maybe for 39647-97-7

Synasia Inc

Contact:17316303296

Address:240 Amboy Ave
SuZhou Yacoo Science Co., Ltd

website:https://www.yacoo.com.cn/en/

Contact:86-512-87182055

Address:No.112 Xinqing Rd, Suzhou Industrial Park, China, 215125, China
Zibo Linzi Darong Fine Chemical Co., Ltd(expird)

Contact:86-532-67773200; 15689126900

Address:Qidu town,Linzi district,Zibo city,Shandong province,China
shanghai jinshan pharmaceutical Co.,Ltd

Contact:021-57363011，13681638167

Address:No. 7966 Tingfeng Road,Jinshan,Shanghai,China
Yueyang Hudex Pharmaceuticals Ltd.

Contact:0730-8748800

Address:Wujiang Bridge，Yueyang Economy & Technology Development Zone

Relevant to this article

The first flights of a molecular shuttle transporting elements: Easy one-pot formation of organic cyclic arsanes, stibanes and bismutanes

Doi:10.1002/chem.200802007
(2009)
Studies aimed at the total synthesis of the antitumor antibiotic cochleamycin A. An enantioselective biosynthesis-based pathway to the AB bicyclic core

Doi:10.1021/ol0102592
(2002)
Nickel Catalyzed Intermolecular Carbonyl Addition of Aryl Halide

Doi:10.1002/ejoc.201901367
(2019)
New pyrazole derivatives containing 1,2,4-triazoles and benzoxazoles as potent antimicrobial and analgesic agents

Doi:10.1016/j.ejmech.2012.12.057
(2013)
Short Enantioselective Total Synthesis of (-)-Rhazinilam Using a Gold(I)-Catalyzed Cyclization

Doi:10.1021/acs.orglett.7b02210
(2017)
Chemoselective Glycosylations (Part 1): Differences in Size of Anomeric Leaving Groups can be Exploited in Chemoselective Glycosylations

Doi:10.1016/0040-4039(95)01222-4
(1995)

Article Doi