Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 1. (±)-(3-Pyridinylbicycloheptyl)alkanoic acids

DOI: 10.1021/jm00110a006

Source and publish data:

Journal of Medicinal Chemistry p. 1790 - 1797 (1991)

Update date:2022-09-26

Topics:

Authors:

Bhagwat Bhagwat

Gude Gude

Cohen Cohen

Lee Lee

Furness Furness

Clarke Clarke

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Article abstract of DOI:10.1021/jm00110a006

The design, synthesis, and in vitro pharmacology of a new class of compounds exerting both thromboxane receptor antagonist and thromboxane synthase inhibtory activities is described. [(3-Pyridinyl)bicycloheptyl]alkanoic acid 9 and its analogues, designed

Full text of DOI:10.1021/jm00110a006

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