Water-soluble, core-modified porphyrins as novel, longer-wavelength-absorbing sensitizers for photodynamic therapy. II. Effects of core heteroatoms and meso-substituents on biological activity

DOI: 10.1021/jm0103662

Source and publish data:

Journal of Medicinal Chemistry p. 449 - 461 (2002)

Update date:2022-08-05

Topics:

Authors:

Hilmey, David G.

Abe, Masako

Nelen, Marina I.

Stilts, Corey E.

Baker, Gary A.

Baker, Sheila N.

Bright, Frank V.

Davies, Sherry R.

Gollnick, Sandra O.

Oseroff, Allan R.

Gibson, Scott L.

Hilf, Russell

Detty, Michael R.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm0103662

Water-soluble, core-modified porphyrins were prepared and evaluated as sensitizers for photodynamic therapy (PDT). The addition of an aromatic aldehyde to 2,5-dilithiothiophene or -selenophene gave diol 3 as a nearly equimolar mixture of meso and d,1 dias

Full text of DOI:10.1021/jm0103662

Products guided by the article

Product name:2,5-bis[(4-trifluoromethylphenyl)hydroxymethyl]thiophene

Cas No:398514-71-1

R&D Labs maybe for 398514-71-1

Dalian Join King Biochemical Tech. Co., Ltd.

Contact:0411 39216206

Address:814 First State Blvd
BAODING SINO-CHEM INDUSTRY CO.,LTD

Contact:0312-5956088

Address:NO.8 FUXING ROAD,CHINA
Shanghai Puda Chemical Co.,Ltd

Contact:+86+571+56565965

Address:10F Haiyue Building,Danfeng Road,Binjiang District,Hangzhou,China
PharmOrgsyn

Contact:+86-21-38228826

Address:Room 505 Building 2, No 3377 Kangxin Highway, Shanghai, Republic China
Acorn PharmaTech Co., Ltd

Contact:86-25-58619180

Address:Nanjing High-Tech Zone 10 Xinghuo Road Pukou District Nanjing, Jiangsu 210061 The People's Republic of China

Relevant to this article

Synthesis of Aryldiazoacetates through Palladium(0)-Catalyzed Deacylative Cross-Coupling of Aryl Iodides with Acyldiazoacetates

Doi:10.1002/anie.201407653
(2014)
Doi:10.1016/0040-4020(75)87075-X
(1975)
Synthesis of potential bisphenol A substitutes by isomerising metathesis of renewable raw materials

Doi:10.1039/c7gc00553a
(2017)
Design and synthesis of Pfmrk inhibitors as potential antimalarial agents.

Doi:10.1016/S0960-894X(01)00578-9
(2001)
Anion stability in stannylium, oxonium, and silylium salts of the weakly coordinating anion [C₆F₄-1,2-{B(C₆F₅)₂}₂(μ-OCH₃)]^-

Doi:10.1021/om010750x
(2002)
Pd-Catalyzed Alkene Difunctionalization Reactions of Malonate Nucleophiles: Synthesis of Substituted Cyclopentanes via Alkene Aryl-Alkylation and Akenyl-Alkylation

Doi:10.1021/acs.orglett.9b01258
(2019)

Article Doi