First synthesis of (+)- and (-)-elvirol based on an enzymatic function

Article abstract of DOI:10.1016/S0957-4166(01)00447-5

A highly enantioselective synthesis of versatile chiral synthons possessing one stereogenic center, (S)- and (R)-4-aryl-5-hydroxy-(2E)-pentenoate 3 was achieved based on the enzymatic reaction of (±)-4 with commercially available lipase 'OF-360' from Cand