Stereoselective syntheses of syn 5-[1-hydroxy-2-(2-bromo-phenyl)-ethyl]-5-methyl-5H-furan-2-one and syn 5-[1-hydroxy-2-(2-methoxy-phenyl)-ethyl]-5-methyl-5H-furan-2-one

DOI: 10.1016/S0040-4020(01)00975-9

Source and publish data:

Tetrahedron p. 9597 - 9605 (2001)

Update date:2022-08-03

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Authors:

Redero, Elena

Sandoval, Celso

Bermejo, Francisco

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Article abstract of DOI:10.1016/S0040-4020(01)00975-9

The aldol condensation of 2-(tert-butyldimethylsilyloxy)-5-methyl-furan 4 with several phenylacetaldehydes led stereoselectively to the syn or the anti aldols under fluoride- or Lewis-acid-promoted conditions. However low yields are obtained due to the fo

Full text of DOI:10.1016/S0040-4020(01)00975-9

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