Synthesis of chiral crown ethers having bromoarylene moieties on their rim. Anomalous behavior of racemic substrates in cyclization to crown ethers

Article abstract of DOI:10.1246/bcsj.69.2595

Bis(binaphtho)-22-crown-5 and bis(binaphtho)-22-crown-4, having bromoarylene moities on their rim, were prepared from (R)- and (5)-2,2′-dihydroxy-1,1′-binaphthyl. An acyclic diol, bridged by two (R)-binaphthyl moieties, underwent cyclization reaction with