Bioorganic and Medicinal Chemistry p. 6221 - 6236 (2004)
Update date:2022-09-26
Topics:
Kupchinsky, Stanley
Centioni, Sara
Howard, Tiffany
Trzupek, John
Roller, Shane
Carnahan, Virginia
Townes, Heather
Purnell, Bethany
Price, Carly
Handl, Heather
Summerville, Kaitlin
Johnson, Kimberly
Toth, James
Hudson, Stephen
Kiakos, Konstantinos
Hartley, John A.
Lee, Moses
The synthesis, DNA binding properties, and in vitro and in vivo anticancer activity of fifteen achiral seco-cyclopropylindoline (or achiral seco-CI) analogs (5a-o) of CC-1065 and the duocarmycins are described. The achiral seco-CI analogs contain a 4-hydr
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Doi:10.1016/S0957-4166(03)00442-7
(2003)Doi:10.1134/S1070427208030221
(2008)Doi:10.1021/ja017563a
(2002)Doi:10.1016/j.tetasy.2006.07.037
(2006)Doi:10.1002/1099-0682(200103)2001:3<805::AID-EJIC805>3.0.CO;2-2
(2001)Doi:10.1021/ic000769c
(2001)
