Silica triflate as an efficient reagent for the chemoselective formylation of alcohols

Article abstract of DOI:10.1080/10426500601160710

Silica triflate, as a new and stable silica-based reagent, is prepared by a reaction of silica gel with trifluoromethane sulfonyl chloride at room temperature. This reagent can be used for the efficient and selective formylation of alcohols in the presence of phenols in a relatively short reaction time and high yields under heterogeneous reaction conditions.