Enantioselective synthesis of (2S)-2-(4-phosphonophenylmethyl)-3-aminopropanoic acid suitably protected for peptide synthesis

DOI: 10.1016/S0040-4039(02)00004-7

Source and publish data:

Tetrahedron Letters p. 1417 - 1419 (2002)

Update date:2022-08-03

Topics:

Authors:

Liu, Wang-Qing

Olszowy, Catherine

Bischoff, Laurent

Garbay, Christiane

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Article abstract of DOI:10.1016/S0040-4039(02)00004-7

Protected D-β-2-(4-phosphono) phenylalanine was prepared by a multistep synthesis, involving the diastereoselective alkylation of a chiral enolate. This new compound can be further incorporated into peptidic backbone by means of solid-phase peptide synthe

Full text of DOI:10.1016/S0040-4039(02)00004-7

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