EPC synthesis of 5-substituted 2-oxo-cyclopentanecarboxylates via conjugate addition of cuprates to asymmetric shielded 2-oxo-cyclopentenecarboxylates

Article abstract of DOI:10.1016/0040-4039(95)01537-R

Asymmetric shielded 2-oxo-cyclopentenecarboxylates 6n and 6x were prepared by trans-esterification of 2-oxo-cyclopentanecarboxylate 2 with camphor derived concave alcohols 1n and 1x and by subsequent introduction of a double bond via phenylselenides. Dias