N,N'-Dialkyl-1,2-bis(hydroxyphenyl)ethylenediamines and N,N'-Dialkyl-4,5-bis(4-hydroxyphenyl)imidazolidines: Syntheses and Evaluation of Their Mammary Tumor Inhibiting Activity

DOI: 10.1021/jm00349a013

Source and publish data:

Journal of Medicinal Chemistry p. 832 - 837 (1982)

Update date:2022-08-05

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Authors:

Angerer, Erwin von

Egginger, Guenter

Kranzfelder, Gerhard

Bernhauer, Horst

Schoenenberger, Helmut

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Article abstract of DOI:10.1021/jm00349a013

Diastereomeric N,N'-dialyl-1,2-bis(hydroxyphenyl)ethylenediamines (5) were synthesized and tested for their affinity for the estradiol receptor.Only the (+/-)-1,2-bis(4-hydroxyphenyl)ethylenediamines with the alkyl groups C3H7 <(+/-)-5c, K_a=1.1

Full text of DOI:10.1021/jm00349a013

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