Synthesis of a pyrrolo[1,4]benzodiazepinequinone

Article abstract of DOI:10.1080/00397919908086212

Condensation of 3,6-dimethoxy-2-nitrobenzoyl chloride with L-proline methyl ester afforded amide 4, which underwent reductive cyclization with iron(II) sulfate and ammonium hydroxide to yield pyrrolobenzodiazepine 5. Oxidation of 5 with ammonium cerium(IV

Full text of DOI:10.1080/00397919908086212

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Synthesis of a
Pyrrolo[1,4]Benzodiazepinequinon
Ricardo A. Tapia a , Cesar R. Centella a & Jaime A.
Valderrama a
a Facultad de Química, Pontificia Universidad
Católica de Chile, Casilla 306, Santiago, 22, Chile
Published online: 17 Sep 2007.
To cite this article: Ricardo A. Tapia , Cesar R. Centella & Jaime A. Valderrama
(1999) Synthesis of a Pyrrolo[1,4]Benzodiazepinequinone, Synthetic Communications:
An International Journal for Rapid Communication of Synthetic Organic Chemistry,
29:12, 2163-2168, DOI: 10.1080/00397919908086212
To link to this article: http://dx.doi.org/10.1080/00397919908086212
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