Synthesis of 3′- and 5′-nitrooxy pyrimidine nucleoside nitrate esters: "Nitric oxide donor" agents for evaluation as anticancer and antiviral agents

Article abstract of DOI:10.1021/jm020299r

A group of 3′-O-nitro-2′-deoxyuridines, 3′-O -nitro-2′-deoxycytidines and 5′-O-nitro-2′-deoxyuridines possessing a variety of substituents (H, Me, F, I) at the C-5 position were synthesized for evaluation as anticancer/antiviral agents that have the abili