An intramolecular case of sharpless kinetic resolution: Total synthesis of laulimalide

DOI: 10.1002/1521-3773(20011015)40:20<3842::AID-ANIE3842>3.0.CO;2-R

Source and publish data:

Angewandte Chemie - International Edition p. 3842 - 3846 (2001)

Update date:2022-08-04

Topics:

Authors:

Mulzer, Johann

Oehler, Elisabeth

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/1521-3773(20011015)40:20<3842::AID-ANIE3842>3.0.CO;2-R

The microtubule-stabilizing antitumor agent laulimalide (1) has been obtained in by new synthetic route. The carbon skeleton was assembled by means of Julia-Kocienski (C16-C17) and Horner-Wadsworth-Emmons (C21-C22) olefinations. Still-Gennari olefination

Full text of DOI:10.1002/1521-3773(20011015)40:20<3842::AID-ANIE3842>3.0.CO;2-R

Products guided by the article

Product name:Methanesulfonic acid (1S,3R)-1-(tert-butyl-dimethyl-silanyloxymethyl)-3-methyl-5-phenylsulfanyl-pentyl ester

Cas No:527742-93-4

R&D Labs maybe for 527742-93-4

Hangzhou Gangjin Chemical Co.,Ltd.(expird)

Contact:+86-571-85109780

Address:707 Zhejiang Minhang Bldg., No.290 Zhongshan North Road, Hangzhou 310003, China
Shanghai Cheerchem Co., Ltd.

Contact:86-21-50966856

Address:Building 5,300 Chuanzhan Road,Pudong New District,Shanghai
ShangHai Original Economy-Trade Develop Co.,Ltd.,

Contact:86-21-68552131

Address:shanghai
PINGYUAN SIHUAN PHARMACEUTICAL CO., LTD

Contact:+86-531-55696072

Address:#2766,yinxiu Road, Economic Development Zone, Pingyuan Country, Shandong Province, China.
Arshine Pharmaceutical Co., Limited

website:http://www.cnarshine.com

Contact:0731-88503671

Address:Room 1109.Block C3, Lugu Enterprise Plaza,No.27 Wenxuan Road,Changsha National Hi-Tech Industrial Development Zone,Hunan ,P.R.China

Relevant to this article

Design and structure-activity relationships of 2-alkyl-3-aminomethyl-6-(3-methoxyphenyl)-7-methyl-8-(2-fluorobenzyl) imidazolo[1,2-α]pyrimid-5-ones as potent GnRH receptor antagonists

Doi:10.1021/jm0205402
(2003)
In situ generation of nitroso compounds from catalytic hydrogen peroxide oxidation of primary aromatic amines and their one-pot use in hetero-Diels-Alder reactions

Doi:10.1002/ejoc.200700368
(2007)
Macrocyclic ligands with partially fluorinated sidearms: Synthesis and metal ion complexation

Doi:10.1016/S0040-4020(00)00248-9
(2000)
Palladium-Catalyzed Sequential C-H Activation/Amination with Diaziridinone: An Approach to Indoles

Doi:10.1021/acs.orglett.1c01043
(2021)
Chiral protic imidazolium salts with a (-)-menthol fragment in the cation: Synthesis, properties and use in the Diels-Alder reaction

Doi:10.1039/c7ra12176h
(2018)
Doi:10.1021/jo00930a006
(1974)

Article Doi