
Journal of Medicinal Chemistry p. 1299 - 1304 (1977)
Update date:2022-08-04
Topics:
Jones
Holtz
Bicking
Cragoe Jr.
A series of 7-(N-alkylmethanesulfonamido)heptanoic acids has been prepared which represents an extension of the 8-aza-11,12-secoprostaglandin studies. The compounds mimic the natural prostaglandins in that they markedly stimulate cAMP formation in the mouse ovary assay.
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