11,12-Secoprostaglandins. 4. 7-(N-alkylmethanesulfonamido)heptanoic acids

DOI: 10.1021/jm00220a014

Source and publish data:

Journal of Medicinal Chemistry p. 1299 - 1304 (1977)

Update date:2022-08-04

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Authors:

Jones Jones

Holtz Holtz

Bicking Bicking

Cragoe Jr.

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Article abstract of DOI:10.1021/jm00220a014

A series of 7-(N-alkylmethanesulfonamido)heptanoic acids has been prepared which represents an extension of the 8-aza-11,12-secoprostaglandin studies. The compounds mimic the natural prostaglandins in that they markedly stimulate cAMP formation in the mouse ovary assay.

Full text of DOI:10.1021/jm00220a014

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