Journal of Medicinal Chemistry p. 2216 - 2226 (2003)
Update date:2022-08-05
Topics:
Kim, Myoung Goo
Bodor, Erik T.
Wang, Chen
Harden, T. Kendall
Kohn, Harold
Expedient syntheses of C(8) substituted 1-azabicyclo[3.3.1]non-3-enes and C(8) substituted 1-azabicyclo[3.3.1]nonan-4-ones are reported to begin with 2,5-disubstituted pyridines. Catalytic reduction of the pyridine to the piperidine followed by treatment
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