The Design of Inner-Functionalised U-Shaped Cavity Molecules: Role of Phenyl Substituents at the 1,3-Position of Isobenzofurans and Oxa-Bridges in the Dienophile as Stereochemical Controlling Elements

Article abstract of DOI:10.1055/s-1997-700

1,3-Diphenylisobenzofuran reacts with fused mono- and bis-norbornenes, 7-oxanorbornenes and cyclobutene-1,2-diesters with high stereospecificity whereas the corresponding isobenzofuran cycloadditions produce mixtures; this provides a basis for regulating