Tetrahedron Letters p. 2601 - 2604 (2003)
Update date:2022-08-05
Topics:
Xu, Lianhong
Zhang, Lijun
Bryant, Clifford M.
Kim, Choung U.
AN1057A/B has shown potent activity against MRSA. A novel and concise route to the synthesis of its heterocycle core 2,5-diamino-5,6-dihydro-1H-pyrimidine-4-one is described. This methodology allows the synthesis of an array of analogs with different amin
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