Tetrahedron p. 12349 - 12360 (1998)
Update date:2022-09-26
Topics: Chemical reactions Analysis Experimental Design Comparative study Synthetic Approaches
Cledera, Pilar
Avendano, Carmen
Menendez, J. Carlos
The transformation of 3-arylmethylenepiperazine-2,5-diones (1) into 1- arylmethylene-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-diones (2) was studied. Four synthetic methods were compared, namely direct condensation with the product of the reaction be
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