Amino acid derived latent isocyanates: Irreversible inactivation of porcine pancreatic elastase and human leukocyte elastase

DOI: 10.1021/jm00380a010

Source and publish data:

Journal of Medicinal Chemistry p. 204 - 209 (1985)

Update date:2022-08-05

Topics:

Authors:

Groutas Groutas

Abrams Abrams

Theodorakis

Kasper Kasper

Rude Rude

Badger Badger

Ocain Ocain

Miller Miller

Moi Moi

Brubaker

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Article abstract of DOI:10.1021/jm00380a010

Several amino acid derived azolides (I) have been synthesized and investigated for their inhibitory activity toward human leukocyte elastase and porcine pancreatic elastase. The inhibitory activity was found to be dependent on the nature of the precursor

Full text of DOI:10.1021/jm00380a010

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