σ Ligands with subnanomolar affinity and preference for the σ2 binding site. 2. Spiro-joined benzofuran, isobenzofuran, and benzopyran piperidines

DOI: 10.1021/jm00011a020

Source and publish data:

Journal of Medicinal Chemistry p. 2009 - 2017 (1995)

Update date:2022-08-02

Topics:

Authors:

Moltzen Moltzen

Perregaard

Meier Meier

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Article abstract of DOI:10.1021/jm00011a020

Spiro[isobenzofuran-1(3H),4'-piperidines] and the corresponding benzofuran and benzopyran derivatives have been synthesized and evaluated as σ ligands. The compounds are related to Lu 28-179 (1'[4-[1(4fluorophenyl)-1H-indol-3- yl]-1-butyl]spiro[isobenzofu

Full text of DOI:10.1021/jm00011a020

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